Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide

BACKGROUND: Inherited DNA-repair gene mutations are more prevalent in men with advanced prostate cancer than previously thought, but their clinical implications are not fully understood. OBJECTIVE: To investigate the clinical significance of germline DNA-repair gene alterations in men with metastati...

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Udgivet i:Eur Urol
Main Authors: Antonarakis, Emmanuel S., Lu, Changxue, Luber, Brandon, Liang, Chao, Wang, Hao, Chen, Yan, Silberstein, John L., Piana, Danilo, Lai, Zhao, Chen, Yidong, Isaacs, William B., Luo, Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045965/
https://ncbi.nlm.nih.gov/pubmed/29439820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2018.01.035
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