In vivo tropism of Salmonella Typhi toxin to cells expressing a multiantennal glycan receptor

Typhoid fever is a life-threatening disease, but little is known about the molecular bases for its unique clinical presentation. Typhoid toxin, a unique virulence factor of Salmonella Typhi (the cause of typhoid fever), recapitulates in an animal model many symptoms of typhoid fever. Typhoid toxin b...

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Veröffentlicht in:Nat Microbiol
Hauptverfasser: Yang, Yi-An, Lee, Sohyoung, Zhao, Jun, Thompson, Andrew J., McBride, Ryan, Tsogtbaatar, Buyankhishig, Paulson, James C., Nussinov, Ruth, Deng, Lingquan, Song, Jeongmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045816/
https://ncbi.nlm.nih.gov/pubmed/29203881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0076-4
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