Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi

Salmonella Typhi is an exclusive human pathogen that causes typhoid fever. Typhoid toxin is a S. Typhi virulence factor that can reproduce most of the typhoid fever symptoms in experimental animals. Toxicity depends on toxin binding to terminally sialylated glycans on surface glycoproteins. Human gl...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Deng, Lingquan, Song, Jeongmin, Gao, Xiang, Wang, Jiawei, Yu, Hai, Chen, Xi, Varki, Nissi, Naito-Matsui, Yuko, Galán, Jorge E., Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258231/
https://ncbi.nlm.nih.gov/pubmed/25480294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.057
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