Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases

Brain metastases are devastating complications of cancer. The blood–brain barrier (BBB), which protects the normal brain, morphs into an inadequately characterized blood–tumor barrier (BTB) when brain metastases form, and is surrounded by a neuroinflammatory response. These structures contribute to...

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Publicado no:Nat Commun
Main Authors: Gril, Brunilde, Paranjape, Anurag N., Woditschka, Stephan, Hua, Emily, Dolan, Emma L., Hanson, Jeffrey, Wu, Xiaolin, Kloc, Wojciech, Izycka-Swieszewska, Ewa, Duchnowska, Renata, Pęksa, Rafał, Biernat, Wojciech, Jassem, Jacek, Nayyar, Naema, Brastianos, Priscilla K., Hall, O. Morgan, Peer, Cody J., Figg, William D., Pauly, Gary T., Robinson, Christina, Difilippantonio, Simone, Bialecki, Emilie, Metellus, Philippe, Schneider, Joel P., Steeg, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045677/
https://ncbi.nlm.nih.gov/pubmed/30006619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05030-w
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