TMIC-19. ASTROCYTIC S1P3 SIGNALING MODULATES BLOOD-TUMOR BARRIER PERMEABILITY IN BRAIN METASTASES

Breast cancer brain metastases are incurable. The blood-brain barrier (BBB) is a multicellular dynamic structure regulating exchanges between the blood and the central nervous system. As cancer cells colonize the brain, the BBB evolves into a blood-tumor barrier (BTB) and remains a potent barrier to...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Gril, Brunilde, Paranjape, Anurag N, Woditschka, Stephan, Hanson, Jeffrey, Wu, Xiaolin, Duchnowska, Renata, Brastianos, Priscilla K, Peer, Cody, Figg, William D, Pauly, Gary T, Schneider, Joel P, Steeg, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693203/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1009
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