The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence

Alcohol dependence (AD) frequently co-occurs with major depressive disorder (MDD). While this comorbidity is associated with an increase in disease burden, worse treatment outcomes, and greater economic costs, the underlying neurobiology remains poorly understood. A recent large-scale GWAS of MDD ha...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Muench, Christine, Schwandt, Melanie, Jung, Jeesun, Cortes, Carlos R., Momenan, Reza, Lohoff, Falk W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045574/
https://ncbi.nlm.nih.gov/pubmed/30006604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0184-9
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