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Dopamine Transporter Gene Methylation is Associated with Nucleus Accumbens Activation during Reward Processing in Healthy but not Alcohol-Dependent Individuals
BACKGROUND: Alcohol's reinforcement is mediated by dopamine signaling in the ventral striatum, which is modulated by the dopamine transporter (DAT). We hypothesized that methylomic variation in the DAT gene (SLC6A3) affects DAT expression thus contributing to differences in brain reward circuit...
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| Publicado no: | Alcohol Clin Exp Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010188/ https://ncbi.nlm.nih.gov/pubmed/29030974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13526 |
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