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Structural Insight of Amyloidogenic Intermediates of Human Insulin

[Image: see text] Engaging Raman spectroscopy as a primary tool, we investigated the early events of insulin fibrilization and determined the structural content present in oligomer and protofibrils that are formed as intermediates in the fibril formation pathway. Insulin oligomer, as obtained upon i...

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Publicat a:ACS Omega
Autors principals: Dolui, Sandip, Roy, Anupam, Pal, Uttam, Saha, Achintya, Maiti, Nakul C.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045404/
https://ncbi.nlm.nih.gov/pubmed/30023834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01776
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