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Structural Insight of Amyloidogenic Intermediates of Human Insulin

[Image: see text] Engaging Raman spectroscopy as a primary tool, we investigated the early events of insulin fibrilization and determined the structural content present in oligomer and protofibrils that are formed as intermediates in the fibril formation pathway. Insulin oligomer, as obtained upon i...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Dolui, Sandip, Roy, Anupam, Pal, Uttam, Saha, Achintya, Maiti, Nakul C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045404/
https://ncbi.nlm.nih.gov/pubmed/30023834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01776
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