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Predictive Model for the Sequence-Dependent Fluorogenic Response of Forced-Intercalation Peptide Nucleic Acid

[Image: see text] The forced-intercalation peptide nucleic acid (FIT-PNA) concept, introduced by Seitz and co-workers, is based on replacing a nucleobase of the PNA sequence with a cyanine dye (such as thiazole orange). The cyanine dye is thus a surrogate base that is forced to intercalate in the du...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Peled, Itamar, Yavin, Eylon
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045369/
https://ncbi.nlm.nih.gov/pubmed/30023882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00184
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