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Empirical Valence Bond Simulations Suggest a Direct Hydride Transfer Mechanism for Human Diamine Oxidase

[Image: see text] Diamine oxidase (DAO) is an enzyme involved in the regulation of cell proliferation and the immune response. This enzyme performs oxidative deamination in the catabolism of biogenic amines, including, among others, histamine, putrescine, spermidine, and spermine. The mechanistic de...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Maršavelski, Aleksandra, Petrović, Dušan, Bauer, Paul, Vianello, Robert, Kamerlin, Shina Caroline Lynn
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2018
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044848/
https://ncbi.nlm.nih.gov/pubmed/30023875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00346
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