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Exploring Structural Relationships between Bioactive and Commercial Chemical Space and Developing Target Hypotheses for Compound Acquisition

[Image: see text] Analog series were systematically extracted from more than 650 000 bioactive compounds originating from medicinal chemistry and screening sources and more than 3.6 million commercial compounds that were not biologically annotated. Then, analog series-based (ASB) scaffolds were gene...

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Opis bibliograficzny
Wydane w:ACS Omega
Główni autorzy: Cerchia, Carmen, Dimova, Dilyana, Lavecchia, Antonio, Bajorath, Jürgen
Format: Artigo
Język:Inglês
Wydane: American Chemical Society 2017
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044811/
https://ncbi.nlm.nih.gov/pubmed/30023563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01338
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