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Difatty Acyl-Conjugated Linear and Cyclic Peptides for siRNA Delivery
[Image: see text] A number of amphiphilic difatty acyl linear and cyclic R(5)K(2) peptide conjugates were synthesized by solid-phase peptide methods to enhance the interaction with the hydrophobic cellular phospholipid bilayer and to improve siRNA delivery and silencing. Binding to siRNA molecules w...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044792/ https://ncbi.nlm.nih.gov/pubmed/30023535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00741 |
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