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Comparative Study of 5′- and 3′-Linked CpG–Antigen Conjugates for the Induction of Cellular Immune Responses

[Image: see text] Conjugation of CpG to an antigen induces a stronger immune response compared to that of the mixture. This study compares the in vitro immunostimulatory activity of CpG conjugated via either its 5′ or 3′ end to the model antigen ovalbumin (OVA). CpG modified with an amine at either...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Kramer, Katrin, Young, Sarah L., Walker, Greg F.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044624/
https://ncbi.nlm.nih.gov/pubmed/30023513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00368
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