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Comparative Study of 5′- and 3′-Linked CpG–Antigen Conjugates for the Induction of Cellular Immune Responses

[Image: see text] Conjugation of CpG to an antigen induces a stronger immune response compared to that of the mixture. This study compares the in vitro immunostimulatory activity of CpG conjugated via either its 5′ or 3′ end to the model antigen ovalbumin (OVA). CpG modified with an amine at either...

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Detalles Bibliográficos
Publicado en:ACS Omega
Main Authors: Kramer, Katrin, Young, Sarah L., Walker, Greg F.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2017
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044624/
https://ncbi.nlm.nih.gov/pubmed/30023513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00368
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