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Nanoparticle System Based on Amino-Dextran as a Drug Delivery Vehicle: Immune-Stimulatory CpG-Oligonucleotide Loading and Delivery

The aim of this study is to prepare and characterize an amino-dextran nanoparticle (aDNP) platform and investigate two loading strategies for unmethylated cytosine-phosphate-guanine (CpG) oligonucleotide. aDNP was prepared by desolvation of amino-dextran followed by the chemical crosslinking of amin...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Nguyen, Hien V., Campbell, Katrin, Painter, Gavin F., Young, Sarah L., Walker, Greg F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760314/
https://ncbi.nlm.nih.gov/pubmed/33260874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121150
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