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Application of a New Scaffold Concept for Computational Target Deconvolution of Chemical Cancer Cell Line Screens

[Image: see text] Target deconvolution of phenotypic assays is a hot topic in chemical biology and drug discovery. The ultimate goal is the identification of targets for compounds that produce interesting phenotypic readouts. A variety of experimental and computational strategies have been devised t...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Kunimoto, Ryo, Dimova, Dilyana, Bajorath, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2017
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044569/
https://ncbi.nlm.nih.gov/pubmed/30023635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00215
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