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Fibroblast Growth Factor 23 and Klotho Contribute to Airway Inflammation

Circulating levels of fibroblast growth factor (FGF) 23 are associated with systemic inflammation and increased mortality in chronic kidney disease. α-klotho, a co-receptor for FGF23, is downregulated in chronic obstructive pulmonary disease (COPD). However, whether FGF23 and klotho-mediated FGFR ac...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Krick, Stefanie, Grabner, Alexander, Baumlin, Nathalie, Yanucil, Christopher, Helton, Scott, Grosche, Astrid, Sailland, Juliette, Geraghty, Patrick, Viera, Liliana, Russell, Derek W., Wells, J. Michael, Xu, Xin, Gaggar, Amit, Barnes, Jarrod, King, Gwendalyn D., Campos, Michael, Faul, Christian, Salathe, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044452/
https://ncbi.nlm.nih.gov/pubmed/29748308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00236-2018
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