Inhibition of hypoxia-associated response and kynurenine production in response to hyperbaric oxygen as mechanisms involved in protection against experimental cerebral malaria

Cerebral malaria (CM) is a multifactorial syndrome involving an exacerbated proinflammatory status, endothelial cell activation, coagulopathy, hypoxia, and accumulation of leukocytes and parasites in the brain microvasculature. Despite significant improvements in malaria control, 15% of mortality is...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Bastos, Marcele F., Kayano, Ana Carolina A. V., Silva-Filho, João Luiz, Dos-Santos, João Conrado K., Judice, Carla, Blanco, Yara C., Shryock, Nathaniel, Sercundes, Michelle K., Ortolan, Luana S., Francelin, Carolina, Leite, Juliana A., Oliveira, Rafaella, Elias, Rosa M., Câmara, Niels O. S., Lopes, Stefanie C. P., Albrecht, Letusa, Farias, Alessandro S., Vicente, Cristina P., Werneck, Claudio C., Giorgio, Selma, Verinaud, Liana, Epiphanio, Sabrina, Marinho, Claudio R. F., Lalwani, Pritesh, Amino, Rogerio, Aliberti, Julio, Costa, Fabio T. M.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044055/
https://ncbi.nlm.nih.gov/pubmed/29558201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700844R
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