Inhibition of hypoxia-associated response and kynurenine production in response to hyperbaric oxygen as mechanisms involved in protection against experimental cerebral malaria

Cerebral malaria (CM) is a multifactorial syndrome involving an exacerbated proinflammatory status, endothelial cell activation, coagulopathy, hypoxia, and accumulation of leukocytes and parasites in the brain microvasculature. Despite significant improvements in malaria control, 15% of mortality is...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Bastos, Marcele F., Kayano, Ana Carolina A. V., Silva-Filho, João Luiz, Dos-Santos, João Conrado K., Judice, Carla, Blanco, Yara C., Shryock, Nathaniel, Sercundes, Michelle K., Ortolan, Luana S., Francelin, Carolina, Leite, Juliana A., Oliveira, Rafaella, Elias, Rosa M., Câmara, Niels O. S., Lopes, Stefanie C. P., Albrecht, Letusa, Farias, Alessandro S., Vicente, Cristina P., Werneck, Claudio C., Giorgio, Selma, Verinaud, Liana, Epiphanio, Sabrina, Marinho, Claudio R. F., Lalwani, Pritesh, Amino, Rogerio, Aliberti, Julio, Costa, Fabio T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044055/
https://ncbi.nlm.nih.gov/pubmed/29558201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700844R
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