The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation

BACKGROUND: The steroid hormone estrogen (17-β-estradiol, E2) provides neuroprotection against cerebral ischemic injury by activating estrogen receptors. The novel estrogen receptor G protein-coupled receptor 30 (GPR30) is highly expressed in the brain and provides acute neuroprotection against stro...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhang, Zengli, Qin, Pei, Deng, Youliang, Ma, Zhi, Guo, Hang, Guo, Haiyun, Hou, Yushu, Wang, Shiquan, Zou, Wangyuan, Sun, Yanyuan, Ma, Yulong, Hou, Wugang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043971/
https://ncbi.nlm.nih.gov/pubmed/30001721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1246-x
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