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Terpene Moiety Enhancement by Overexpression of Geranyl(geranyl) Diphosphate Synthase and Geraniol Synthase Elevates Monomeric and Dimeric Monoterpene Indole Alkaloids in Transgenic Catharanthus roseus

Catharanthus roseus is the sole source of two of the most important anticancer monoterpene indole alkaloids (MIAs), vinblastine and vincristine and their precursors, vindoline and catharanthine. The MIAs are produced from the condensation of precursors derived from indole and terpene secoiridoid pat...

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Publicat a:Front Plant Sci
Autors principals: Kumar, Sarma R., Shilpashree, H. B., Nagegowda, Dinesh A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043680/
https://ncbi.nlm.nih.gov/pubmed/30034406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2018.00942
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