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Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation

Apoptosis is an important physiological process in development and disease. Apoptotic cells (ACs) are a major source of self-antigens, but ACs usually evade immune responses. The mechanism by which ACs repress T cell adaptive immune responses is poorly understood. T cell activation is finely regulat...

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Publicat a:Sci Rep
Autors principals: Yakoub, Abraam M., Schulz, Ralph, Seiffert, Martina, Sadek, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043626/
https://ncbi.nlm.nih.gov/pubmed/30002409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28901-0
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