Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy

Diabetic nephropathy (DN) is the major cause of end-stage renal failure and is associated with increased morbidity and mortality compared with other causes of renal diseases. We previously found that Smad1 plays a critical role in the development of DN both in vitro and in vivo. However, functional...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Ono, Hiroyuki, Abe, Hideharu, Sakurai, Akiko, Ochi, Arisa, Tominaga, Tatsuya, Tamaki, Masanori, Kishi, Seiji, Murakami, Taichi, Nagai, Kojiro, Kohashi, Masayuki, Doi, Toshio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043613/
https://ncbi.nlm.nih.gov/pubmed/30002389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28439-1
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