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Genetic variation of SORBS1 gene is associated with glucose homeostasis and age at onset of diabetes: A SAPPHIRe Cohort Study

The SORBS1 gene plays an important role in insulin signaling. We aimed to examine whether common single-nucleotide polymorphisms (SNPs) of SORBS1 are associated with prevalence and incidence of diabetes, age at onset of diabetes, and the related traits of glucose homeostasis. A total of 1135 sibling...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Tien-Jyun, Wang, Wen-Chang, Hsiung, Chao A., He, Chih-Tsueng, Lin, Ming-Wei, Sheu, Wayne Huey-Herng, Chang, Yi-Cheng, Quertermous, Tom, Chen, Yii-Der Ida, Rotter, Jerome I., Chuang, Lee-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043583/
https://ncbi.nlm.nih.gov/pubmed/30002559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28891-z
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