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Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

Proprotein convertase subtilisin/kexin type 2 (PCSK2) is a prohormone processing enzyme involved in insulin and glucagon biosynthesis. We previously found the genetic polymorphism of PCSK2 on chromosome 20 was responsible for the linkage peak of several glucose homeostasis parameters. The aim of thi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Tien-Jyun, Chiu, Yen-Feng, Sheu, Wayne H-H., Shih, Kuang-Chung, Hwu, Chii-Min, Quertermous, Thomas, Jou, Yuh-Shan, Kuo, Shan-Shan, Chang, Yi-Cheng, Chuang, Lee-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660384/
https://ncbi.nlm.nih.gov/pubmed/26607656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14380
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