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Computation predicts rapidly adapting mechanotransduction currents cannot account for tactile encoding in Merkel cell-neurite complexes

Distinct firing properties among touch receptors are influenced by multiple, interworking anatomical structures. Our understanding of the functions and crosstalk of Merkel cells and their associated neurites—the end organs of slowly adapting type I (SAI) afferents—remains incomplete. Piezo2 mechanic...

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Publicat a:PLoS Comput Biol
Autors principals: Gerling, Gregory J., Wan, Lingtian, Hoffman, Benjamin U., Wang, Yuxiang, Lumpkin, Ellen A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042796/
https://ncbi.nlm.nih.gov/pubmed/29958280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006264
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