The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells

Prostate carcinoma contain foci of neuroendocrine transdifferentiation, resulting in an increase of androgen-independent neuroendocrine-like (NE) tumor cells, whose number significantly correlates with tumor aggressiveness and thus lower survival rate. Neuroendocrine transdifferentiation of prostate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dankert, Jaroslaw Thomas, Wiesehöfer, Marc, Czyrnik, Elena Dilara, Singer, Bernhard B., von Ostau, Nicola, Wennemuth, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042731/
https://ncbi.nlm.nih.gov/pubmed/30001402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200472
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