In healthy volunteers, taking flucloxacillin with food does not compromise effective plasma concentrations in most circumstances

It is usually recommended that flucloxacillin is given on an empty stomach. The aim of this study was to compare total and free flucloxacillin concentrations after oral flucloxacillin, given with and without food, based on contemporary pharmacokinetic and pharmacodynamic targets. Flucloxacillin 1000...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gardiner, Sharon J., Drennan, Philip G., Begg, Ronald, Zhang, Mei, Green, Jared K., Isenman, Heather L., Everts, Richard J., Chambers, Stephen T., Begg, Evan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042703/
https://ncbi.nlm.nih.gov/pubmed/30001392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199370
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