Design and development of ICCA as a dual inhibitor of GPIIb/IIIa and P-selectin receptors

BACKGROUND: The impact of upregulation of platelet membrane glycoprotein (GP)IIb/IIIa and P-selectin on the onset of arterial thrombosis, venous thrombosis, and cancer encourages to hypothesize that dual inhibitor of GPIIb/IIIa and P-selectin receptors should simultaneously inhibit arterial thrombos...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Chen, Haiyan, Lu, An, Zhang, Xiaoyi, Gui, Lin, Wang, Yaonan, Wu, Jianhui, Feng, Hua, Peng, Shiqi, Zhao, Ming
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042529/
https://ncbi.nlm.nih.gov/pubmed/30022809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169238
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