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Relation of high neuroticism with increased methylation of the BDNF gene

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has an important function in neuroplasticity and neuronal development. It is suggested that increased methylation of the BDNF gene resulting in decreased BDNF activity is associated with depression. Meanwhile, neuroticism is...

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Publicado en:Neuropsychiatr Dis Treat
Autores principales: Shirata, Toshinori, Suzuki, Akihito, Matsumoto, Yoshihiko, Takahashi, Nana, Noto, Keisuke, Goto, Kaoru, Otani, Koichi
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042484/
https://ncbi.nlm.nih.gov/pubmed/30022827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S169787
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