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Relation of high neuroticism with increased methylation of the BDNF gene

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has an important function in neuroplasticity and neuronal development. It is suggested that increased methylation of the BDNF gene resulting in decreased BDNF activity is associated with depression. Meanwhile, neuroticism is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychiatr Dis Treat
Hauptverfasser: Shirata, Toshinori, Suzuki, Akihito, Matsumoto, Yoshihiko, Takahashi, Nana, Noto, Keisuke, Goto, Kaoru, Otani, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042484/
https://ncbi.nlm.nih.gov/pubmed/30022827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S169787
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