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Relation of high neuroticism with increased methylation of the BDNF gene

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has an important function in neuroplasticity and neuronal development. It is suggested that increased methylation of the BDNF gene resulting in decreased BDNF activity is associated with depression. Meanwhile, neuroticism is...

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Detalles Bibliográficos
Publicado en:Neuropsychiatr Dis Treat
Main Authors: Shirata, Toshinori, Suzuki, Akihito, Matsumoto, Yoshihiko, Takahashi, Nana, Noto, Keisuke, Goto, Kaoru, Otani, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042484/
https://ncbi.nlm.nih.gov/pubmed/30022827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S169787
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