Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth

BACKGROUND: The disruption of E-cadherin-mediated adhesion is considered an important driver of tumor progression. Nevertheless, numerous studies have demonstrated that E-cadherin promotes growth- or invasion-related signaling, contrary to the prevailing notion. During tumor progression, epithelial...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Rea, Katia, Roggiani, Francesca, De Cecco, Loris, Raspagliesi, Francesco, Carcangiu, Maria Luisa, Nair-Menon, Joyce, Bagnoli, Marina, Bortolomai, Ileana, Mezzanzanica, Delia, Canevari, Silvana, Kourtidis, Antonis, Anastasiadis, Panos Z., Tomassetti, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042237/
https://ncbi.nlm.nih.gov/pubmed/29996940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0796-1
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