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Developmental and Tissue-Specific Regulation of Hepatocyte Nuclear Factor 4-α (HNF4-α) Isoforms in Rodents

Hepatocyte nuclear factor 4-α (HNF4-α) regulates expression of a number of genes in several metabolic organs. The HNF4-α gene has two promoters and encodes at least nine isoforms through differential splicing. In mouse liver, transcription initiates at promoter 2 (P2) during fetal life, but switches...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Dean, Samena, Tang, Justin I., Seckl, Jonathan R., Nyirenda, Moffat J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042024/
https://ncbi.nlm.nih.gov/pubmed/20635575
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