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The role of enasidenib in the treatment of mutant IDH2 acute myeloid leukemia
Recurrent mutations affecting cellular metabolism and epigenetic regulation are implicated in the pathogenesis of acute myeloid leukemia (AML). Isocitrate dehydrogenase 2 (IDH2) gene mutations are described in 12% of patients with AML and 5% of patients with myelodysplastic syndromes. IDH2 enzyme is...
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| Gepubliceerd in: | Ther Adv Hematol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
SAGE Publications
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6041864/ https://ncbi.nlm.nih.gov/pubmed/30013764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718777467 |
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