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KL1333, a Novel NAD(+) Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), one of the most common maternally inherited mitochondrial diseases, is caused by mitochondrial DNA mutations that lead to mitochondrial dysfunction. Several treatment options exist, including supplementation with CoQ...

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Bibliografische gegevens
Gepubliceerd in:Front Neurol
Hoofdauteurs: Seo, Kang-Sik, Kim, Jin-Hwan, Min, Ki-Nam, Moon, Jeong-A, Roh, Tae-Chul, Lee, Mi-Jung, Lee, Kang-Woo, Min, Ji-Eun, Lee, Young-Mock
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041391/
https://ncbi.nlm.nih.gov/pubmed/30026729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00552
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