KL1333, a Novel NAD(+) Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), one of the most common maternally inherited mitochondrial diseases, is caused by mitochondrial DNA mutations that lead to mitochondrial dysfunction. Several treatment options exist, including supplementation with CoQ...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Seo, Kang-Sik, Kim, Jin-Hwan, Min, Ki-Nam, Moon, Jeong-A, Roh, Tae-Chul, Lee, Mi-Jung, Lee, Kang-Woo, Min, Ji-Eun, Lee, Young-Mock
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041391/
https://ncbi.nlm.nih.gov/pubmed/30026729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00552
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