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Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis

Myosin X (Myo10), an actin-associated molecular motor, has a clear role in filopodia induction and cell migration in vitro, but its role in vivo in mammals is not well understood. Here, we investigate the role of Myo10 in melanocyte lineage and melanoma induction. We found that Myo10 knockout (Myo10...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tokuo, Hiroshi, Bhawan, Jag, Coluccio, Lynne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041326/
https://ncbi.nlm.nih.gov/pubmed/29993000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28717-y
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