Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57

Paramyxoviridae, a large family of enveloped viruses harboring a nonsegmented negative-sense RNA genome, include important human pathogens as measles, mumps, respiratory syncytial virus (RSV), parainfluenza viruses, and henipaviruses, which cause some of the deadliest emerging zoonoses. There is no...

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Published in:Sci Rep
Main Authors: Piacentini, Sara, La Frazia, Simone, Riccio, Anna, Pedersen, Jens Z., Topai, Alessandra, Nicolotti, Orazio, Rossignol, Jean-Francois, Santoro, M. Gabriella
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041319/
https://ncbi.nlm.nih.gov/pubmed/29992955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28172-9
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