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Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors
Free fatty acid receptor 2 (FFAR2, also named GPR43), is activated by short-chain fatty acids (SCFAs), such as butyrate, that are produced when gut bacteria ferment dietary fiber. FFAR2 has been suggested to regulate colonic inflammation, which is a major risk factor for the development of colon can...
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| Publicado no: | Int J Cancer |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6041131/ https://ncbi.nlm.nih.gov/pubmed/29524208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31366 |
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