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Targeting phospholipase D in cancer, infection and neurodegenerative disorders

Lipid second messengers have essential roles in cellular function and contribute to the molecular mechanisms that underlie inflammation, malignant transformation, invasiveness, neurodegenerative disorders, and infectious and other pathophysiological processes. The phospholipase D (PLD) isoenzymes PL...

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書目詳細資料
發表在:Nat Rev Drug Discov
Main Authors: Brown, H. Alex, Thomas, Paul G., Lindsley, Craig W.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040825/
https://ncbi.nlm.nih.gov/pubmed/28209987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.252
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