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Targeting phospholipase D in cancer, infection and neurodegenerative disorders

Lipid second messengers have essential roles in cellular function and contribute to the molecular mechanisms that underlie inflammation, malignant transformation, invasiveness, neurodegenerative disorders, and infectious and other pathophysiological processes. The phospholipase D (PLD) isoenzymes PL...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Brown, H. Alex, Thomas, Paul G., Lindsley, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040825/
https://ncbi.nlm.nih.gov/pubmed/28209987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.252
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