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Dentate gyrus mossy cells control spontaneous convulsive seizures and spatial memory

Temporal lobe epilepsy (TLE) is characterized by debilitating, recurring seizures and an increased risk for cognitive deficits. Mossy cells (MCs) are key neurons in the hippocampal excitatory circuit, and the partial loss of MCs is a major hallmark of TLE. We investigated how MCs contribute to spont...

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Foilsithe in:Science
Main Authors: Bui, Anh D., Nguyen, Theresa M., Limouse, Charles, Kim, Hannah K., Szabo, Gergely G., Felong, Sylwia, Maroso, Mattia, Soltesz, Ivan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040648/
https://ncbi.nlm.nih.gov/pubmed/29449490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan4074
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