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Dentate gyrus mossy cells control spontaneous convulsive seizures and spatial memory

Temporal lobe epilepsy (TLE) is characterized by debilitating, recurring seizures and an increased risk for cognitive deficits. Mossy cells (MCs) are key neurons in the hippocampal excitatory circuit, and the partial loss of MCs is a major hallmark of TLE. We investigated how MCs contribute to spont...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bui, Anh D., Nguyen, Theresa M., Limouse, Charles, Kim, Hannah K., Szabo, Gergely G., Felong, Sylwia, Maroso, Mattia, Soltesz, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040648/
https://ncbi.nlm.nih.gov/pubmed/29449490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan4074
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