Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease

PURPOSE: Dense deposit disease (DDD) is caused by dysregulation of the alternative pathway of the complement cascade and characterized by electron-dense deposits in the kidney glomerular basement membrane (GBM) and drusen in Bruch's membrane (BrM). Complement factor H (fH) and factor properdin...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Song, Delu, Mohammed, Imran, Bhuyan, Rupak, Miwa, Takashi, Williams, Allison Lesher, Gullipalli, Damodar, Sato, Sayaka, Song, Ying, Dunaief, Joshua L., Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040236/
https://ncbi.nlm.nih.gov/pubmed/30025090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24133
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