Region-Specific Effects of Immunotherapy With Antibodies Targeting α-synuclein in a Transgenic Model of Synucleinopathy

Synucleinopathies represent a group of neurodegenerative disorders which are characterized by intracellular accumulation of aggregated α-synuclein. α-synuclein misfolding and oligomer formation is considered a major pathogenic trigger in these disorders. Therefore, targeting α-synuclein species repr...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Kallab, Martin, Herrera-Vaquero, Marcos, Johannesson, Malin, Eriksson, Fredrik, Sigvardson, Jessica, Poewe, Werner, Wenning, Gregor K., Nordström, Eva, Stefanova, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039792/
https://ncbi.nlm.nih.gov/pubmed/30022929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00452
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