ロード中...
Na(V)1.4 DI-S4 periodic paralysis mutation R222W enhances inactivation and promotes leak current to attenuate action potentials and depolarize muscle fibers
Hypokalemic periodic paralysis is a skeletal muscle disease characterized by episodic weakness associated with low serum potassium. We compared clinical and biophysical effects of R222W, the first hNa(V)1.4 domain I mutation linked to this disease. R222W patients exhibited a higher density of fibers...
保存先:
| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039468/ https://ncbi.nlm.nih.gov/pubmed/29991727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28594-5 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|