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Domain III S4 in closed-state fast inactivation: Insights from a periodic paralysis mutation
Heterologous expression of sodium channel mutations in hypokalemic periodic paralysis reveals 2 variants on channel dysfunction. Charge-reducing mutations of voltage sensing S4 arginine residues alter channel gating as typically studied with expression in mammalian cells. These mutations also produc...
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Publicado no: | Channels (Austin) |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594372/ https://ncbi.nlm.nih.gov/pubmed/25483590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.958924 |
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