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The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification

Haematopoietic cells arise from endothelial cells within the dorsal aorta of the embryo via a process called the endothelial-haematopoietic transition (EHT). This process crucially depends on the transcription factor RUNX1 which rapidly activates the expression of genes essential for haematopoietic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gilmour, Jane, Assi, Salam A., Noailles, Laura, Lichtinger, Monika, Obier, Nadine, Bonifer, Constanze
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039467/
https://ncbi.nlm.nih.gov/pubmed/29991720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28506-7
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