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Directed, Palladium(II)-Catalyzed Intermolecular Aminohydroxylation of Alkenes Using a Mild Oxidation System

A palladium(II)-catalyzed β,γ-aminohydroxylation reaction of non-conjugated alkenyl carbonyl compounds has been developed. This reaction utilizes a cleavable bidentate directing group to achieve regioselective aminopalladation. The resulting chelation-stabilized alkylpalladium(II) intermediate is th...

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Pubblicato in:Org Lett
Autori principali: Zeng, Tian, Liu, Zhen, Schmidt, Michael A., Eastgate, Martin D., Engle, Keary M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039249/
https://ncbi.nlm.nih.gov/pubmed/29888604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01440
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