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Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes Kaposi’s sarcoma(1,2), a cancer that commonly affects patients with AIDS(3) and which is endemic in sub-Saharan Africa(4). The KSHV capsid is highly pressurized by its double-stranded DNA genome, as are the capsids of the eight other human herpes...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Dai, Xinghong, Gong, Danyang, Lim, Hanyoung, Jih, Jonathan, Wu, Ting-Ting, Sun, Ren, Zhou, Z. Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039102/
https://ncbi.nlm.nih.gov/pubmed/29342139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25438
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